It looks like many people seems to wonder what’s the difference as well as similarities between Femara Vs Clomid taken in consideration that these are 2 compounds both considered effective at treating infertility, both are coming in form of oral pills and both are considered anti estrogens and plus to that, doing research about anabolic steroids, you may often find these 2 compounds being mentioned.
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Similarities Femara VS Clomid
As it was earlier mentioned, Femara vs Clomid do have various things in common and due to these similarities, these 2 compounds are often compared to each other.
- Both are anti-estrogens dealing with estrogen related issues.
- Both Femara and Clomid are helpful at treating infertility among women.
- Both Femara and Clomid come as oral pills administered by mouth.
- Both compounds are effective at lowering estrogen in breast tissues.
- Both these drugs are having some common side effects.
- Both Femara and Clomid are used by men too, either during cycle for dealing with estrogen related side effects caused by anabolic steroids, or as a PCT medication after the anabolic steroid cycle to help recover the body’s HPTA after a cycle.
Differences Femara VS Clomid
As much as you can see, there are many similarities between Femara and Clomid, nonetheless, they are actually very different drugs and that’s why there are numerous things that can be mentioned when analyzing the differences between Femara VS Clomid.
- To start off, Femara active substance is Letrozole whilst Clomid active substance is Clomiphene.
- Despite both being anti estrogens, Femara is Aromatase Inhibitor (AI) but Clomid is Selective Estrogen Receptor Modulator (SERM).
- With this being said, they are both dealing with estrogen hormones, but they have completely different mechanisms of actions. Femara is working by inhibiting aromatase and suppressing overall estrogen production, but Clomid is working by selectively inhibiting estrogen receptors (by binding to them) in some parts of the body and selectively activating estrogen receptors (by binding to them) in other parts.
- Despite Clomid being able to help with estrogen related side effects to some degree, is by far not as effective as Femara.
- Despite Femara being able to recover HPTA of an anabolic steroid user to some degree, is by far not as effective as Clomid.
- Due to earlier mentioned reasons, Clomid is by far most preferred as a PCT medication (and very rarely for estrogenic protection) whilst Femara is by far most preferred as an estrogenic protection (and very rarely for PCT plans).
- They are having some similar side effects, but at the same time, Femara and Clomid still have different side effects. Most commonly, Femara side effects are related to low estrogen levels whilst Clomid side effects are related to emotions of a person.
- Both are used by women in medical settings, but Femara (Letrozole) mostly by postmenopausal women with breast cancer whilst Clomid (Clomiphene) mostly by women with ovulatory dysfunction.
Femara Vs Clomid – Which One to Choose?
Keep in mind that there are also other similarities and differences between Femara Vs Clomid. In the end, the biggest similarity is that they are both dealing with estrogen related issues, but the biggest difference is that they are dealing with those issues in completely different methods.
If you’re wondering which one to choose then it highly depends on various factors. There’s not a better compound than others overall. There might be one better than another for a specific person with a specific need.
- For example, if you’re running aromatizable (wet) anabolic steroids then Femara (Letrozole) is going to be by far a better compound to deal with estrogen related side effects than Clomid (Clomiphene).
- But when you stop the use of the exact same anabolic steroid cycle and you need to go through an effective PCT plan, then Clomid is considered to be a far better drug for restarting your HPTA than Femara.
At the same time, women dealing with breast cancers might find Femara way better, whilst those who are not fertile could find Clomid better.
In the end, as mentioned, it highly depends on many different factors. If you require one of them for a medical reason – talk to your doctor to tell you which one is better. If you need it for steroid cycles then generally (for most people ) – Clomid for PCT, Femara for estrogen control on cycle.
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